SCHEMBL7398296

SCHEMBL7398296

CC(Sc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.66
CYP2C19 P33261 3/20 0.66
HSD17B10 Q99714 2/20 0.66
TSHR P16473 1/20 0.60
HPGD P15428 2/20 0.54
LMNA P02545 3/20 0.52
NPSR1 Q6W5P4 3/20 0.52
THRB P10828 2/20 0.52
PLA2G1B P04054 1/20 0.52
NPY1R P25929 1/20 0.52
NPY2R P49146 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ATG4B Q9Y4P1 1/20 0.52
TYMP P19971 1/20 0.51
MMP2 P08253 1/20 0.48
MMP8 P22894 1/20 0.48
MMP14 P50281 1/20 0.48
PPARA Q07869 3/20 0.48
SDCBP O00560 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11538170 0.94 HSD17B10 (0.59) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL11538173 0.90 HSD17B10 (0.54) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL13438254 0.82 TSHR (0.58) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL10455020 0.82 KDM4E (0.47) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL11574943 0.82 HPGD (0.57) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL5110593 0.82 GAA (0.53) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL10455022 0.82 KDM4E (0.47) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL1931354 0.81 KDM4E (0.51) HSD17B10LMNANPSR1SMN1; SMN2L3MBTL1
SCHEMBL7048451 0.80 MEN1 (0.51) CYP2C9CYP2C19HSD17B10TSHRHPGD
SCHEMBL875038 0.80 KDM4E (0.46) CYP2C9CYP2C19HSD17B10TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
CN-110229333-B Synthetic method of polyimide 湘潭大学 2022-02-15 CN disclosed
US-11147788-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2021-10-19 US disclosed
US-10934244-B2 Compounds for use in treating neuromuscular disorders NMD PHARMA A/S (DK) 2021-03-02 US disclosed
US-10385028-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2019-08-20 US disclosed
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS (DK) 2019-06-20 US disclosed
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS 2019-06-20 US disclosed
US-20190183863-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20180099920-A1 COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS NMD PHARMA APS (DK) 2018-04-12 US disclosed
US-20180099920-A1 COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS NMD PHARMA APS (DK) 2018-04-12 US disclosed
US-5583142-A TROPANYL-PHENYL OR NAPHTHYL-CARBOXYLATE OR CARBAMYLATE COMPOUNDS; LEARNING ENHANCEMENT FIDIA S.P.A. (IT) 1996-12-10 US disclosed
EP-0650486-A1 NEW ANALGESIC AND NOOTROPIC DRUGS FIDIA S.p.A. (IT) 1995-05-03 EP disclosed
WO-1994001435-A1 NEW ANALGESIC AND NOOTROPIC DRUGS FIDIA S.P.A. (IT) 1994-01-20 WO disclosed
US-4528286-A Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) 1985-07-09 US disclosed
US-4268516-A [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents PFIZER INC. (US) 1981-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 CYP2C9 4788/4885CYP2C19 4866/4885HSD17B10 2497/4885
US-10934244-B2 Compounds for use in treating neuromuscular disorders CPT1B, CLCN2, TNNC1 CYP2C9 4866/4885CYP2C19 4874/4885HSD17B10 2401/4885
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 CYP2C9 4788/4885CYP2C19 4866/4885HSD17B10 2497/4885
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders CPT1B, CLCN2, CACNB1 CYP2C9 4031/4885CYP2C19 4208/4885HSD17B10 1321/4885
US-20180099920-A1 COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS CPT1B, CLCN2, TNNC1 CYP2C9 4866/4885CYP2C19 4874/4885HSD17B10 2401/4885
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 CYP2C9 4788/4885CYP2C19 4866/4885HSD17B10 2497/4885
US-11147788-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 CYP2C9 4788/4885CYP2C19 4866/4885HSD17B10 2497/4885
US-10385028-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 CYP2C9 4788/4885CYP2C19 4866/4885HSD17B10 2497/4885
US-20190183863-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 CYP2C9 4788/4885CYP2C19 4866/4885HSD17B10 2497/4885
US-20190183833-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 CYP2C9 4788/4885CYP2C19 4866/4885HSD17B10 2497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.