Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455022 | 0.82 | KDM4E (0.47) | KDM4ELMNAEPHX1HSD17B10CYP2C9 | |
| SCHEMBL5110593 | 0.82 | GAA (0.53) | KDM4ELMNAHSD17B10CYP2C9CYP2C19 | |
| SCHEMBL10455020 | 0.82 | KDM4E (0.47) | KDM4ELMNAEPHX1HSD17B10CYP2C9 | |
| SCHEMBL11574943 | 0.82 | HPGD (0.57) | KDM4ELMNAHSD17B10CYP2C9CYP2C19 | |
| SCHEMBL1931354 | 0.81 | KDM4E (0.51) | KDM4ELMNAEPHX1HSD17B10ALDH1A1 | |
| SCHEMBL7398296 | 0.80 | CYP2C9 (0.66) | KDM4ELMNAHSD17B10CYP2C9CYP2C19 | |
| SCHEMBL7048451 | 0.80 | MEN1 (0.51) | KDM4ELMNAEPHX1HSD17B10CYP2C9 | |
| SCHEMBL2553786 | 0.78 | HPGD (0.55) | KDM4ELMNAHSD17B10CYP2C9CYP2C19 | |
| SCHEMBL1178110 | 0.78 | EPHX1 (0.45) | KDM4ELMNAEPHX1ALDH1A1NPSR1 | |
| SCHEMBL11516166 | 0.77 | ALDH1A1 (0.51) | KDM4ELMNAEPHX1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | MMP9, MMP12, MMP10 | KDM4E 4398/4885LMNA 2726/4885EPHX1 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.