Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400027 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2BALDH1A1MAPTCYP2D6 | |
| SCHEMBL7402217 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BALDH1A1MAPTCYP2D6 | |
| SCHEMBL6181293 | 0.81 | CHRM2 (0.55) | ALDH1A1MAPTGPR119TSHRGFER | |
| SCHEMBL6793505 | 0.80 | HRH3 (0.47) | ITGB3ITGA2BCYP2D6CYP3A4CYP2C9 | |
| SCHEMBL7396321 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1MAPTCYP2D6 | |
| SCHEMBL27475914 | 0.76 | ALDH1A1 (0.54) | ITGB3ITGA2BALDH1A1MAPTCYP2D6 | |
| SCHEMBL7399390 | 0.75 | MAPT (0.45) | ITGB3ITGA2BALDH1A1MAPTCYP2D6 | |
| SCHEMBL7400434 | 0.75 | ALDH1A1 (0.58) | ITGB3ITGA2BALDH1A1MAPTGFER | |
| SCHEMBL7399572 | 0.74 | MAPT (0.46) | ITGB3ITGA2BALDH1A1MAPTCYP2D6 | |
| SCHEMBL381997 | 0.74 | CYP11B1 (0.48) | GPR119CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |