Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395116 | 0.88 | HRH3 (0.50) | HRH3HRH1HRH2ITGB3ITGA2B | |
| SCHEMBL7334450 | 0.88 | HRH3 (0.57) | HRH3HRH1MAPTFAAHHRH2 | |
| SCHEMBL7403373 | 0.86 | FAAH (0.54) | BRD4HRH3PDE3BPDE3AHRH1 | |
| SCHEMBL7325096 | 0.85 | HRH3 (0.49) | HRH3HRH1MAPTFAAHMETAP1 | |
| SCHEMBL8889829 | 0.85 | HRH3 (0.58) | HRH3HRH1MAPTFAAHHRH2 | |
| SCHEMBL7397026 | 0.83 | FAAH (0.51) | BRD4HRH3HRH1MAPTFAAH | |
| SCHEMBL8889153 | 0.81 | KDM4E (0.47) | HRH3MAPTITGB3ITGA2B | |
| SCHEMBL7334443 | 0.81 | SMN1; SMN2 (0.56) | MAPT | |
| SCHEMBL7398346 | 0.79 | SMN1; SMN2 (0.44) | HRH3MAPTMETAP1ITGB3ITGA2B | |
| SCHEMBL7403379 | 0.78 | SMN1; SMN2 (0.55) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825184-B1 | Heterocyclic derivatives as platelet aggregation inhibitors | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |