Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403145 | 0.99 | HTR1A (0.51) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7401257 | 0.91 | HTR1A (0.49) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7403340 | 0.83 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7401521 | 0.83 | HTR3E (0.48) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7403329 | 0.78 | HTR3E (0.53) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7362880 | 0.78 | HTR2C (0.66) | HTR1AHTR2CHTR3A | |
| SCHEMBL7370137 | 0.77 | HTR2C (0.63) | HTR1AHTR2CHTR3A | |
| SCHEMBL7398383 | 0.75 | HTR3E (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7365939 | 0.74 | HTR3E (0.54) | HTR1AHTR2CHTR3EHTR3BHTR3A | |
| SCHEMBL7362654 | 0.74 | HTR2A (0.50) | HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014381-A1 | ETHER DERIVATIVES OF PYRROLO[1,2-A]QUINOXALINES, METHOD FOR PRODUCING THEM AND THEIR USE IN THERAPY | UNIVERSITE DE CAEN BASSE-NORMANDIE (FR) | 2001-03-01 | — | — | WO | disclosed |