Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7398703

CCOC(=O)CC(C)NC(=O)Cn1ccn(-c2ccc(C(=N)N)cc2)c1=O.O=C(O)C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 11/20 0.39
ITGA2B P08514 11/20 0.39
ELANE P08246 2/20 0.38
F2 P00734 5/20 0.38
F10 P00742 4/20 0.38
PRSS1 P07477 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7401536 0.89 ITGB3 (0.49) ITGB3ITGA2BF2
Trifluoroacetic Acid SCHEMBL7399230 0.89 ITGB3 (0.42) ITGB3ITGA2BELANEF2F10
SCHEMBL7401538 0.88 ITGB3 (0.39) ITGB3ITGA2BELANEF2F10
Trifluoroacetic Acid SCHEMBL8539907 0.85 ITGB3 (0.37) ITGB3ITGA2BELANEF2F10
Trifluoroacetic Acid SCHEMBL7404770 0.84 ITGB3 (0.47) ITGB3ITGA2BF2
SCHEMBL8538055 0.84 ITGB3 (0.54) ITGB3ITGA2BF2
SCHEMBL8538690 0.83 F2 (0.47) ITGB3ITGA2BF2F10PRSS1
SCHEMBL9053763 0.82 ITGB3 (0.44) ITGB3ITGA2BF2F10PRSS1
Trifluoroacetic Acid SCHEMBL7397995 0.79 ITGB3 (0.46) ITGB3ITGA2BF2
Trifluoroacetic Acid SCHEMBL7403550 0.78 ITGB3 (0.51) ITGB3ITGA2BF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0715623-B1 PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 1998-09-09 EP claimed
EP-0715623-A1 PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-06-12 EP claimed
US-5430043-A Platelet aggregation inhibitors G. D. SEARLE & CO. (US) 1995-07-04 US claimed
WO-1995006038-A1 PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1995-03-02 WO claimed
EP-0715623-B1 PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 1998-09-09 EP disclosed
EP-0715623-A1 PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-06-12 EP disclosed
US-5489594-A ANTICOAGULANTS G. D. SEARLE & CO. (US) 1996-02-06 US disclosed
US-5430043-A Platelet aggregation inhibitors G. D. SEARLE & CO. (US) 1995-07-04 US disclosed
WO-1995006038-A1 PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1995-03-02 WO disclosed