Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.42 |
| ▸ | F2 | P00734 | 7/20 | 0.36 |
| ▸ | F10 | P00742 | 6/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053763 | 0.94 | ITGB3 (0.44) | ITGB3ITGA2BF2F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7403550 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BF2 | |
| Trifluoroacetic Acid SCHEMBL7398703 | 0.89 | ITGB3 (0.39) | ITGB3ITGA2BF2F10ELANE | |
| SCHEMBL7403554 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2B | |
| SCHEMBL8544627 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BF10 | |
| Trifluoroacetic Acid SCHEMBL8539907 | 0.82 | ITGB3 (0.37) | ITGB3ITGA2BF2F10ELANE | |
| Trifluoroacetic Acid SCHEMBL7404770 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BF2 | |
| SCHEMBL8538690 | 0.80 | F2 (0.47) | ITGB3ITGA2BF2F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7401536 | 0.80 | ITGB3 (0.49) | ITGB3ITGA2BF2 | |
| Trifluoroacetic Acid SCHEMBL7397995 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |