Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.83 |
| ▸ | MAOB | P27338 | 13/20 | 0.83 |
| ▸ | BCHE | P06276 | 2/20 | 0.83 |
| ▸ | ACHE | P22303 | 2/20 | 0.83 |
| ▸ | XDH | P47989 | 2/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7404288 | 0.99 | HRH3 (0.81) | HRH3MAOBBCHEACHEXDH | |
| SCHEMBL1794419 | 0.88 | MAOB (0.68) | HRH3MAOBBCHEACHEXDH | |
| Hydrochloric Acid SCHEMBL11749273 | 0.87 | MAOB (0.67) | HRH3MAOBBCHEACHEXDH | |
| SCHEMBL1793246 | 0.87 | XDH (0.67) | HRH3MAOBBCHEACHEXDH | |
| SCHEMBL1796158 | 0.86 | XDH (0.72) | HRH3MAOBBCHEACHEXDH | |
| Hydrochloric Acid SCHEMBL7329970 | 0.85 | MAOB (0.62) | HRH3MAOBBCHEACHEXDH | |
| SCHEMBL1796898 | 0.85 | XDH (0.72) | HRH3MAOBBCHEACHEXDH | |
| SCHEMBL1797372 | 0.84 | SIGMAR1 (0.66) | HRH3MAOBBCHEACHEXDH | |
| SCHEMBL1797819 | 0.84 | XDH (0.63) | HRH3MAOBBCHEACHEXDH | |
| SCHEMBL1797053 | 0.83 | SIGMAR1 (0.65) | HRH3MAOBBCHEACHEXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637303-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | EP | claimed |
| WO-1993022302-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | claimed |