Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399007 | 1.00 | ACE (0.58) | ACE | |
| Amantadine SCHEMBL7398627 | 0.86 | ACE (0.46) | ACE | |
| Amantadine SCHEMBL7398633 | 0.86 | ACE (0.46) | ACE | |
| SCHEMBL7400828 | 0.85 | MME (0.49) | ACE | |
| SCHEMBL7400830 | 0.85 | MME (0.49) | ACE | |
| SCHEMBL7394102 | 0.81 | MTNR1A (0.44) | ACE | |
| SCHEMBL7394099 | 0.81 | MTNR1A (0.44) | ACE | |
| SCHEMBL7398631 | 0.79 | ACE (0.45) | ACE | |
| SCHEMBL7397890 | 0.79 | ACE (0.36) | ACE | |
| SCHEMBL7395733 | 0.79 | ACE (0.36) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535042-B1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1995-03-29 | — | — | EP | claimed |
| US-5348978-A | Angiotensin converting enzyme inhibitors | FISONS PLC (GB) | 1994-09-20 | — | — | US | claimed |
| EP-0535042-A1 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS. | FISONS PLC (GB) | 1993-04-07 | — | — | EP | claimed |
| WO-1992000276-A2 | ANGIOTENSIS CONVERTING ENZYME INHIBITORS | FISONS PLC (GB) | 1992-01-09 | — | — | WO | claimed |