Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 7/20 | 0.43 |
| ▸ | CPA3 | P15088 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556127 | 1.00 | CPA1 (0.43) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7290455 | 0.85 | CPA1 (0.46) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7399070 | 0.85 | CPA1 (0.46) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7433358 | 0.82 | CPA1 (0.53) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7279259 | 0.77 | CHRNB2 (0.43) | HPGD | |
| SCHEMBL7438742 | 0.77 | REN (0.44) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7290438 | 0.77 | CPA1 (0.44) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7280064 | 0.76 | CPA1 (0.57) | CPA1CPA3CPB1CPB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10449746 | 0.75 | CPA1 (0.55) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7436937 | 0.73 | MME (0.41) | CPA1CPA3CPB1CPB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587767-A1 | HYDROXYAZIDO DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS | SRI INTERNATIONAL (US) | 1994-03-23 | — | — | EP | disclosed |
| WO-1992021696-A1 | HYDROXYAZIDO DERIVATIVES AND RELATED COMPOUNDS AS RENIN INHIBITORS | SRI INTERNATIONAL (US) | 1992-12-10 | — | — | WO | disclosed |