Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609833 | 0.92 | ELANE (0.35) | ELANEPDK2 | |
| SCHEMBL8615680 | 0.89 | ELANE (0.34) | ELANEPDK2 | |
| SCHEMBL7405849 | 0.83 | ELANE (0.33) | ELANE | |
| SCHEMBL8613233 | 0.82 | ELANE (0.34) | ELANE | |
| SCHEMBL7404661 | 0.81 | ELANE (0.33) | ELANE | |
| SCHEMBL7405873 | 0.80 | ELANE (0.35) | ELANE | |
| SCHEMBL8614061 | 0.79 | ELANE (0.42) | ELANE | |
| SCHEMBL8615757 | 0.78 | ELANE (0.33) | ELANE | |
| SCHEMBL7408952 | 0.77 | ELANE (0.33) | ELANE | |
| SCHEMBL7401912 | 0.76 | ELANE (0.37) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997010243-A1 | 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (US) | 1997-03-20 | — | — | WO | disclosed |