Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405849 | 0.97 | ELANE (0.33) | ELANEKDM5A | |
| SCHEMBL8615680 | 0.91 | ELANE (0.34) | ELANE | |
| SCHEMBL8609833 | 0.89 | ELANE (0.35) | ELANE | |
| SCHEMBL8615757 | 0.89 | ELANE (0.33) | ELANE | |
| SCHEMBL7408952 | 0.87 | ELANE (0.33) | ELANE | |
| SCHEMBL8613233 | 0.85 | ELANE (0.34) | ELANE | |
| SCHEMBL7405873 | 0.83 | ELANE (0.35) | ELANE | |
| SCHEMBL8614061 | 0.82 | ELANE (0.42) | ELANE | |
| SCHEMBL7603337 | 0.81 | KDM5A (0.32) | KDM5A | |
| SCHEMBL7401912 | 0.81 | ELANE (0.37) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750550-A | RESPIRATORY SYSTEM DISORDERS | SANOFI (FR) | 1998-05-12 | — | — | US | disclosed |
| WO-1997010243-A1 | 2-(PYRAZOL-5-YL-OXYMETHYL)-1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (US) | 1997-03-20 | — | — | WO | disclosed |