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SCHEMBL8615757

SCHEMBL8615757

CC(C)c1cc(OCCC(C)(C)C(=O)OCc2ccccc2)cc2c1C(=O)N(C(Oc1cc(C(F)(F)F)n[nH]1)c1ccccc1)S2(=O)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 15/20 0.33
▸ DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7408952 0.94 ELANE (0.33) ELANE
SCHEMBL8613233 0.91 ELANE (0.34) ELANE
SCHEMBL7405849 0.90 ELANE (0.33) ELANE
SCHEMBL7404661 0.89 ELANE (0.33) ELANE
SCHEMBL8609833 0.86 ELANE (0.35) ELANE
SCHEMBL7405873 0.86 ELANE (0.35) ELANE
SCHEMBL7401912 0.81 ELANE (0.37) ELANE
SCHEMBL7399082 0.78 ELANE (0.37) ELANE
SCHEMBL7448574 0.76 CARM1 (0.38) ELANE
SCHEMBL7448570 0.75 ELANE (0.42) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750550-A RESPIRATORY SYSTEM DISORDERS SANOFI (FR) 1998-05-12 — — US disclosed