Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666686 | 0.83 | TSHR (0.50) | MCL1TSHRCASP1ACHETRPA1 | |
| SCHEMBL27530049 | 0.81 | MCL1 (0.53) | MCL1TSHRMAPTHPGDHSD17B10 | |
| SCHEMBL2912899 | 0.81 | MCL1 (0.53) | MCL1TSHRMAPTHPGDHSD17B10 | |
| SCHEMBL2122382 | 0.80 | MCL1 (0.57) | MCL1TRPA1MAPTHPGDHSD17B10 | |
| SCHEMBL23712588 | 0.79 | TSHR (0.46) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL8442226 | 0.77 | MAPT (0.50) | MCL1TSHRMAPTHPGDHSD17B10 | |
| SCHEMBL5181271 | 0.76 | MCL1 (0.48) | MCL1TSHRMAPTHPGDHSD17B10 | |
| SCHEMBL7209407 | 0.76 | TSHR (0.48) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL18663454 | 0.76 | TSHR (0.43) | MCL1TSHRCASP1ACHETRPA1 | |
| SCHEMBL10607408 | 0.74 | HSD17B10 (0.50) | MCL1TSHRMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-06-01 | — | — | US | disclosed |
| US-10302821-B2 | Tinting enhancers for hard coat tinting | ESSILOR INTERNATIONAL (FR) | 2019-05-28 | — | — | US | disclosed |
| EP-2992058-B1 | TINTING ENHANCERS FOR HARD COAT TINTING | ESSILOR INT (FR) | 2018-06-06 | — | — | EP | disclosed |
| US-20160077241-A1 | Tinting Enhancers for Hard Coat Tinting | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2016-03-17 | — | — | US | disclosed |
| US-20160010276-A1 | Arylene Carriers for Enhanced Polycarbonate Tinting | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2016-01-14 | — | — | US | disclosed |
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | PADI4, PADI2, PADI6 | MCL1 3436/4885TSHR 3115/4885CASP1 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.