Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.70 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | HTR6 | P50406 | 9/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452199 | 0.89 | HTT (0.59) | PDE4APDE4BPDE4CPDE4DHTR6 | |
| SCHEMBL2270543 | 0.88 | HTR6 (0.60) | PDE4APDE4BPDE4CPDE4DHTR6 | |
| SCHEMBL7359664 | 0.83 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DHTR6 | |
| SCHEMBL2266976 | 0.82 | LMNA (0.56) | PDE4APDE4BPDE4CPDE4DHTR6 | |
| SCHEMBL3965144 | 0.81 | HTR6 (0.70) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL7245919 | 0.81 | HTR6 (0.69) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL3972209 | 0.79 | HTR6 (0.70) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL2001031 | 0.79 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DHTR6 | |
| SCHEMBL28246141 | 0.78 | HTR6 (0.55) | PDE4APDE4BPDE4CPDE4DHTR6 | |
| SCHEMBL20840619 | 0.77 | HTR6 (0.68) | PDE4APDE4BPDE4CPDE4DHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728712-A | 3,4-disubstituted-phenylsulphonamides and their therapeutic use | CHIROSCIENCE LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| WO-1996036611-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |