Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 5/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398146 | 0.84 | CHRM1 (0.47) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL7397407 | 0.81 | CASP3 (0.46) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL7393716 | 0.78 | POLB (0.53) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL15614823 | 0.77 | FABP4 (0.51) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL27436276 | 0.77 | CA1 (0.53) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL16597175 | 0.73 | CA1 (0.46) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL15578799 | 0.72 | FABP4 (0.54) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL25337057 | 0.71 | CA1 (0.66) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL31375594 | 0.71 | HTT (0.68) | POLBCASP3SENP7SENP6CA1 | |
| SCHEMBL22347562 | 0.71 | POLB (0.59) | POLBCASP3SENP7SENP6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330990-A | Antagonists of 5-HT and 5-HT3 receptors, psychological disorders, antinausea | NOVO NORDISK A/S (DK) | 1994-07-19 | — | — | US | disclosed |
| EP-0419397-B1 | Substituted urea compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-06-08 | — | — | EP | disclosed |
| EP-0491770-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-01 | — | — | EP | disclosed |
| WO-1991003475-A1 | SUBSTITUTED UREA COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-03-21 | — | — | WO | disclosed |