Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468694 | 0.82 | TDP1 (0.62) | POLBTDP1NCEH1ALDH1A1HSD17B10 | |
| SCHEMBL596646 | 0.79 | POLB (0.57) | POLBTDP1NCEH1ALDH1A1HSD17B10 | |
| SCHEMBL8474945 | 0.77 | POLB (0.47) | POLBTDP1NCEH1ALDH1A1HSD17B10 | |
| SCHEMBL7477565 | 0.77 | POLB (0.47) | POLBTDP1NCEH1ALDH1A1HSD17B10 | |
| SCHEMBL28358062 | 0.77 | TDP1 (0.66) | TDP1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL14176963 | 0.77 | POLB (0.50) | POLBTDP1NCEH1ALDH1A1HSD17B10 | |
| SCHEMBL18049834 | 0.77 | SMN1; SMN2 (0.49) | POLBTDP1NCEH1ALDH1A1HPGD | |
| SCHEMBL4698955 | 0.75 | POLB (0.52) | POLBTDP1NCEH1ALDH1A1HSD17B10 | |
| SCHEMBL30274454 | 0.75 | POLB (0.52) | POLBTDP1NCEH1ALDH1A1HSD17B10 | |
| SCHEMBL10393003 | 0.75 | POLB (0.44) | POLBALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |
| WO-2000037433-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-06-29 | — | — | WO | disclosed |