Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391888 | 0.81 | LMNA (0.47) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7477565 | 0.80 | POLB (0.47) | POLBSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL11329070 | 0.80 | TDP1 (0.55) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10391498 | 0.75 | SMN1; SMN2 (0.42) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10391499 | 0.75 | SMN1; SMN2 (0.42) | POLBSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL596646 | 0.75 | POLB (0.57) | POLBSMN1; SMN2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7399435 | 0.75 | POLB (0.48) | POLBSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL7468694 | 0.75 | TDP1 (0.62) | POLBSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL10417868 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10417869 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393941-A1 | Naphthalene derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-24 | — | — | EP | disclosed |
| US-4897405-A | Novel naphthalenylalkyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |