Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333337 | 0.85 | HPGD (0.50) | HTTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7404901 | 0.83 | MCL1 (0.64) | MCL1HTTPPARDPTPN7HPGD | |
| SCHEMBL7396688 | 0.82 | LMNA (0.51) | MCL1HTTPPARDPTPN7KDM4E | |
| SCHEMBL1437602 | 0.81 | MAOB (0.58) | ALDH1A1SMN1; SMN2NR4A1 | |
| SCHEMBL6635996 | 0.81 | HTT (0.67) | HTTHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL5262015 | 0.81 | THRA (0.51) | MCL1HTTPPARDKDM4ETHRA | |
| SCHEMBL9457798 | 0.79 | SRD5A2 (0.52) | HTTHPGD | |
| SCHEMBL585812 | 0.79 | MCL1 (0.72) | MCL1PTPN7HPGDKDM4EALDH1A1 | |
| SCHEMBL30025591 | 0.79 | MCL1 (0.72) | MCL1PTPN7HPGDKDM4EALDH1A1 | |
| SCHEMBL3205933 | 0.78 | MCL1 (0.66) | MCL1PTPN7HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |