Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394094 | 1.00 | CASP3 (0.51) | CASP3KMT2AMDM4TP53TNF | |
| SCHEMBL7401573 | 1.00 | CASP3 (0.51) | CASP3KMT2AMDM4TP53TNF | |
| SCHEMBL7394092 | 1.00 | CASP3 (0.51) | CASP3KMT2AMDM4TP53TNF | |
| SCHEMBL7399615 | 1.00 | CASP3 (0.51) | CASP3KMT2AMDM4TP53TNF | |
| SCHEMBL12972482 | 0.85 | CASP3 (0.48) | CASP3KMT2AMDM4TP53TNF | |
| SCHEMBL17826082 | 0.85 | KMT2A (0.56) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL29400679 | 0.85 | KMT2A (0.56) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL13658468 | 0.85 | KMT2A (0.56) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL12928621 | 0.85 | KMT2A (0.56) | CASP3KMT2AMDM4TP53MDM2 | |
| SCHEMBL9186701 | 0.83 | MDM4 (0.59) | CASP3KMT2AMDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624163-B1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMA (IT) | 1998-03-25 | — | — | EP | disclosed |
| EP-0624163-A1 | CYCLIC CALCITONIN DERIVATIVES AND METHOD FOR THEIR PRODUCTION | Smithkline Beecham Farmaceutici S.p.A. (IT) | 1994-11-17 | — | — | EP | disclosed |
| WO-1993015106-A1 | CYCLIC CALCITONINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1993-08-05 | — | — | WO | disclosed |