Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.39 |
| ▸ | TLR3 | O15455 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008330 | 0.72 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL2012701 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL481982 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL2010551 | 0.71 | HIF1A (0.43) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL2011114 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL2011575 | 0.71 | HIF1A (0.48) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL2004771 | 0.70 | ALDH1A1 (0.40) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| SCHEMBL8316383 | 0.70 | TSHR (0.59) | — | |
| SCHEMBL17829468 | 0.69 | ALDH1A1 (0.40) | ALDH1A1HPGDCYP3A4TDP1KDM4E | |
| 6,6-Dimethyl-6H-[1,3]Dioxolo[4,5-G]Chromene SCHEMBL15989695 | 0.69 | ALDH1A1 (0.47) | ALDH1A1HPGDCYP3A4TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919806-A | 8-AMINOPYRANO(2.3-F)BENZO-OXADIAZOLES, THIADIAZOLES AND TRIAZOLES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| WO-1996034871-A1 | BENZOPYRAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-11-07 | — | — | WO | disclosed |
| EP-0693283-A1 | HEART FAILURE REMEDY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |