Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL17095081 | 0.90 | ALDH1A1 (0.42) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| Maleic Acid SCHEMBL17095080 | 0.90 | ALDH1A1 (0.42) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| SCHEMBL17829468 | 0.86 | ALDH1A1 (0.40) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| SCHEMBL2007092 | 0.86 | KDM4E (0.40) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| Malic Acid SCHEMBL17781489 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| SCHEMBL2012483 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| SCHEMBL12580424 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| SCHEMBL17787598 | 0.81 | POLB (0.34) | POLBCYP1A2 | |
| SCHEMBL2010551 | 0.79 | HIF1A (0.43) | ALDH1A1HPGDPOLBKDM4ENPC1 | |
| SCHEMBL12580746 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HPGDPOLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738654-B2 | Method for producing nitrogen-containing heterocyclic N-oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-08-22 | — | — | US | claimed |
| US-20160168161-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2016-06-16 | — | — | US | claimed |
| EP-3026047-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2016-06-01 | — | — | EP | claimed |
| US-20150266887-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROCYCLIC N-OXIDE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-09-24 | — | — | US | claimed |
| US-9738654-B2 | Method for producing nitrogen-containing heterocyclic N-oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9738654-B2 | Method for producing nitrogen-containing heterocyclic N-oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9738654-B2 | Method for producing nitrogen-containing heterocyclic N-oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9738654-B2 | Method for producing nitrogen-containing heterocyclic N-oxide compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-9464095-B2 | Production method of high-purity nitrogen-containing heterocyclic compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-11 | — | — | US | disclosed |
| US-9464095-B2 | Production method of high-purity nitrogen-containing heterocyclic compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-11 | — | — | US | disclosed |
| US-9464095-B2 | Production method of high-purity nitrogen-containing heterocyclic compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20160168161-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2016-06-16 | — | — | US | disclosed |
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1732929-A1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | Nissan Chemical Industries, Ltd. (JP) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005090357-A1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168161-A1 | METHOD FOR PRODUCING HETEROCYCLIC COMPOUND | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NAT10 | ALDH1A1 2486/4885HPGD 93/4885POLB 3181/4885 |
| US-20150266887-A1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROCYCLIC N-OXIDE COMPOUND | NOS3, NOS2, SQOR | ALDH1A1 1143/4885HPGD 79/4885POLB 2412/4885 |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | CBR1, CBR3, SCN8A | ALDH1A1 2087/4885HPGD 2882/4885POLB 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.