Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL28864865 | 1.00 | LMNA (0.40) | LMNA | |
| Acetone SCHEMBL7399779 | 1.00 | LMNA (0.40) | LMNA | |
| Tetrahydrothiophene SCHEMBL9620648 | 0.97 | — | — | |
| Acetic Acid SCHEMBL28746199 | 0.90 | FFAR3 (0.44) | — | |
| Acetic Acid SCHEMBL8037750 | 0.90 | FFAR3 (0.44) | — | |
| Tetrahydrothiophene SCHEMBL9158780 | 0.87 | — | — | |
| Hydrogen Sulfide SCHEMBL28225699 | 0.81 | ALDH1A1 (0.30) | — | |
| Methacrylic Acid SCHEMBL16146329 | 0.81 | TDP1 (0.33) | — | |
| Oxalic Acid SCHEMBL8461222 | 0.80 | — | — | |
| Propionic Acid SCHEMBL27494376 | 0.79 | FFAR3 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034118-A | ENZYME INHIBITOR | GILEAD SCIENCES, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5811450-A | DIAGNOSIS, TREATMENT OF HIV | GILEAD SCIENCES, INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705524-A | ENZYME INHIBITORS; VIRICIDES | GILEAD SCIENCES, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| EP-0789695-A2 | THIEPANE COMPOUNDS INHIBITING AND DETECTING HIV PROTEASE | GILEAD SCIENCES, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996014314-A2 | THIEPANE COMPOUNDS INHIBITING AND DETECTING HIV PROTEASE | GILEAD SCIENCES, INC. (US) | 1996-05-17 | — | — | WO | disclosed |