Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462190 | 0.86 | ITGB3 (0.48) | ITGB3ITGA2BCHRM1TBXAS1DRD4 | |
| SCHEMBL7493723 | 0.81 | ITGB3 (0.50) | ITGB3ITGA2BCHRM1DRD4SLC6A4 | |
| SCHEMBL7399785 | 0.79 | ITGB3 (0.50) | ITGB3ITGA2BCHRM1DRD4SLC6A4 | |
| SCHEMBL27462189 | 0.75 | ITGB3 (0.46) | ITGB3ITGA2BCHRM1TBXAS1DRD4 | |
| SCHEMBL27445589 | 0.74 | ITGB3 (0.49) | ITGB3ITGA2BCHRM1DRD4SLC6A4 | |
| SCHEMBL7493712 | 0.71 | DRD4 (0.61) | ITGB3ITGA2BTBXAS1DRD4SLC6A4 | |
| Hydrochloric Acid SCHEMBL9023742 | 0.71 | DRD4 (0.60) | ITGB3ITGA2BDRD4SLC6A4 | |
| SCHEMBL8701064 | 0.71 | SLC2A1 (0.46) | ITGB3ITGA2BCHRM1DRD4SLC6A4 | |
| SCHEMBL8635007 | 0.71 | DRD4 (0.60) | ITGB3ITGA2BDRD4SLC6A4 | |
| SCHEMBL7400372 | 0.71 | SMN1; SMN2 (0.52) | ITGB3ITGA2BMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |