Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398027 | 0.96 | MAPT (0.56) | SMN1; SMN2NPC1MAPTRAB9AHRH3 | |
| SCHEMBL8890373 | 0.87 | ITGB3 (0.60) | HRH3ITGB3ITGA2BHRH1HRH2 | |
| SCHEMBL7397026 | 0.85 | FAAH (0.51) | SMN1; SMN2NPC1MAPTRAB9AHRH3 | |
| SCHEMBL7334548 | 0.83 | ITGB3 (0.62) | SMN1; SMN2NPC1MAPTRAB9AHRH3 | |
| SCHEMBL7403373 | 0.81 | FAAH (0.54) | SMN1; SMN2NPC1MAPTRAB9AHRH3 | |
| SCHEMBL7395116 | 0.79 | HRH3 (0.50) | HRH3ITGB3ITGA2BHRH1HRH2 | |
| SCHEMBL7401781 | 0.79 | HRH3 (0.51) | SMN1; SMN2NPC1MAPTRAB9AHRH3 | |
| SCHEMBL8634727 | 0.79 | HRH3 (0.55) | SMN1; SMN2NPC1MAPTRAB9AHRH3 | |
| SCHEMBL7392232 | 0.77 | HRH3 (0.54) | SMN1; SMN2NPC1MAPTRAB9AHRH3 | |
| SCHEMBL7400703 | 0.76 | KDM4E (0.49) | SMN1; SMN2NPC1MAPTRAB9AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |