Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396432 | 1.00 | KDM4E (0.73) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| SCHEMBL7398924 | 1.00 | KDM4E (0.73) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| Hydrochloric Acid SCHEMBL7594910 | 0.99 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| Hydrochloric Acid SCHEMBL7395361 | 0.99 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| SCHEMBL14970474 | 0.98 | KDM4E (0.75) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| SCHEMBL7564110 | 0.94 | KDM4E (0.82) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| SCHEMBL7403755 | 0.87 | HRH3 (0.65) | KDM4ESMN1; SMN2ALDH1A1HRH3 | |
| Hydrochloric Acid SCHEMBL7453458 | 0.86 | KDM4E (0.60) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| SCHEMBL1387405 | 0.86 | KDM4E (0.67) | KDM4ESMN1; SMN2ALDH1A1HRH3POLB | |
| Hydrochloric Acid SCHEMBL7397671 | 0.86 | HRH3 (0.64) | KDM4ESMN1; SMN2ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637303-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | EP | claimed |
| WO-1993022302-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | claimed |