Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 10/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405740 | 0.84 | OXTR (0.45) | OXTRAVPR2AVPR1AALDH1A1HSD11B1 | |
| SCHEMBL7484095 | 0.81 | OXTR (0.72) | OXTRAVPR2AVPR1AALDH1A1 | |
| SCHEMBL7508507 | 0.81 | PDE4B (0.51) | OXTRAVPR2AVPR1AALDH1A1HSD11B1 | |
| SCHEMBL7399308 | 0.79 | OXTR (0.51) | OXTRAVPR2AVPR1AALDH1A1HSD11B1 | |
| SCHEMBL7494734 | 0.77 | OXTR (0.49) | OXTRAVPR2AVPR1AALDH1A1HSD11B1 | |
| SCHEMBL7398524 | 0.76 | OXTR (0.60) | OXTRAVPR2AVPR1AALDH1A1HSD11B1 | |
| SCHEMBL7358039 | 0.73 | GPR119 (0.53) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30606457 | 0.73 | GPR119 (0.53) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL18310133 | 0.72 | GPR119 (0.54) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7355186 | 0.72 | GPR119 (0.54) | ALDH1A1PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714299-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714299-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995002405-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-01-26 | — | — | WO | disclosed |