SCHEMBL73999

SCHEMBL73999

O=c1c(-c2ccc(O)cc2)coc2cc(O)c(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 2/20 1.00
ALOX15 P16050 2/20 1.00
MAOA P21397 6/20 0.74
MAOB P27338 6/20 0.74
RAB9A P51151 5/20 0.74
ALDH1A1 P00352 5/20 0.74
SMN1; SMN2 Q16637 5/20 0.74
ALDH2 P05091 5/20 0.74
HDAC6 Q9UBN7 4/20 0.74
NPC1 O15118 4/20 0.74
KDM4E B2RXH2 4/20 0.74
HPGD P15428 4/20 0.74
HSD17B10 Q99714 3/20 0.74
TP53 P04637 3/20 0.74
CYP3A4 P08684 3/20 0.74
MAPT P10636 3/20 0.74
CYP2C9 P11712 3/20 0.74
CYP2C19 P33261 3/20 0.74
AKR1B10 O60218 2/20 0.74
LMNA P02545 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29772934 1.00 ALOX12 (1.00) ALOX12ALOX15MAOAMAOBRAB9A
Isoflavone SCHEMBL3066716 0.89 ALOX12 (0.80) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL28278285 0.88 ALOX15 (0.78) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL12133984 0.88 ALOX15 (0.78) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL678221 0.88 ALOX15 (0.78) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL10563010 0.88 ALOX12 (0.78) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL10563202 0.88 ALOX12 (0.78) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL10559144 0.88 ALOX12 (0.78) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL10561370 0.88 ALOX12 (0.78) ALOX12ALOX15MAOAMAOBRAB9A
SCHEMBL11082015 0.87 ALOX12 (0.77) ALOX12ALOX15MAOAMAOBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP claimed
CN-119439618-A Negative photosensitive resin composition, preparation method thereof and hardening film 深圳市道尔顿电子材料股份有限公司 2025-02-14 CN claimed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US claimed
CN-115612699-B Copolymer membrane, and enzymatic self-assembly synthesis method and application thereof in gas-liquid interface 中国科学院天津工业生物技术研究所 2024-10-25 CN claimed
CN-114557905-B Endogenous cell regulation system and application thereof 昆明美颜美龄生物科技有限公司 2024-05-28 CN claimed
US-20240167066-A1 METHOD FOR PRODUCING DEMETHYLATED COMPOUND DAICEL CORPORATION (JP) 2024-05-23 US claimed
CN-115612403-B Self-assembled strong-adhesion copolymer film, coating method and application 中国科学院天津工业生物技术研究所 2023-12-01 CN claimed
WO-2023284777-A1 COPOLYMER FILM, ENZYME CATALYSIS SELF-ASSEMBLY SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF 中国科学院天津工业生物技术研究所 2023-01-19 WO claimed
CN-115612699-A Copolymer membrane and enzymatic self-assembly synthesis method and application thereof at gas-liquid interface 中国科学院天津工业生物技术研究所 2023-01-17 CN claimed
CN-115612403-A Self-assembly strong-adhesion copolymer film, film coating method and application 中国科学院天津工业生物技术研究所 2023-01-17 CN claimed
US-20110033904-A1 METHOD FOR PREPARING ORTHODIHYDROXYISOFLAVONES USING A BIOTRANSFORMATION SYSTEM AMOREPACIFIC CORPORATION (KP) 2011-02-10 US claimed
EP-2265725-A1 METHOD FOR PREPARING ORTHO-DIHYDROXYISOFLAVONES USING A BIOTRANSFORMATION SYSTEM Amorepacific Corporation (KR) 2010-12-29 EP claimed
WO-2010058936-A2 SKIN EXTERNAL COMPOSITION FOR INHIBITING EPIDERMAL HYPERPROLIFERATION AND ALLEVIATING INFLAMMATORY SKIN DISEASES CONTAINING ORTHO-DIHYDROXYISOFLAVONE DERIVATIVES AMOREPACIFIC CORPORATION (KR) 2010-05-27 WO claimed
WO-2009131264-A1 METHOD FOR PREPARING ORTHO-DIHYDROXYISOFLAVONES USING A BIOTRANSFORMATION SYSTEM AMOREPACIFIC CORPORATION (KR) 2009-10-29 WO claimed
US-20080125481-A1 ISOFLAVONE METABOLITES JOANNOU GEORGE EUSTACE 2008-05-29 US claimed
US-20050222248-A1 Isoflavone metabolites JOANNOU GEORGE E 2005-10-06 US claimed
EP-1189897-A1 ISOFLAVONE METABOLITES G.J. Consultants Pty Ltd (AU) 2002-03-27 EP claimed
WO-2000066576-A1 ISOFLAVONE METABOLITES G.J. CONSULTANTS PTY LTD (AU) 2000-11-09 WO claimed
US-4218489-A Antioxidants, antioxidant compositions and methods of preparing and using same Z-L LIMITED PARTNERSHIP (US) 1980-08-19 US claimed
US-4157984-A Antioxidants, antioxidant compositions and methods of preparing and using same Z-L Limited (US) 1979-06-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222248-A1 Isoflavone metabolites CYP19A1, ESR1, CYP21A2 ALOX12 2799/4885ALOX15 2916/4885MAOA 905/4885
US-20080125481-A1 ISOFLAVONE METABOLITES CYP19A1, ESR1, CYP21A2 ALOX12 2643/4885ALOX15 2835/4885MAOA 870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.