Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399963 | 1.00 | MAPK1 (0.33) | MAPK1SMN1; SMN2GAAF10PPM1B | |
| SCHEMBL7399965 | 1.00 | MAPK1 (0.33) | MAPK1SMN1; SMN2GAAF10PPM1B | |
| SCHEMBL7392441 | 0.83 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAAF10POLB | |
| SCHEMBL7392445 | 0.83 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAAF10POLB | |
| SCHEMBL7392443 | 0.83 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAAF10POLB | |
| SCHEMBL15325061 | 0.83 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAAF10POLB | |
| SCHEMBL8353589 | 0.81 | OPRM1 (0.36) | MAPK1SMN1; SMN2GAAF10POLB | |
| SCHEMBL20348812 | 0.75 | MAPK1 (0.38) | MAPK1SMN1; SMN2GAAPOLBKDM4E | |
| SCHEMBL32674333 | 0.75 | MAPK1 (0.38) | MAPK1SMN1; SMN2GAAPOLBKDM4E | |
| SCHEMBL5104127 | 0.75 | MAPK1 (0.38) | MAPK1SMN1; SMN2GAAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000972-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-01-23 | — | — | WO | disclosed |