Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20348812 | 1.00 | MAPK1 (0.38) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL5104127 | 1.00 | MAPK1 (0.38) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL18346711 | 0.90 | ALOX15 (0.42) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL5116398 | 0.90 | ALOX15 (0.42) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL20348810 | 0.84 | LMNA (0.39) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL7392441 | 0.81 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL7392445 | 0.81 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL15325061 | 0.81 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL7392443 | 0.81 | MAPK1 (0.36) | MAPK1SMN1; SMN2GAALMNAKDM4E | |
| SCHEMBL18358216 | 0.80 | OPRM1 (0.34) | MAPK1SMN1; SMN2GAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042781-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260042781-A1 | Bicyclic Ureas As Kinase Inhibitors | NR0B1, NR2C2, ERBB2 | MAPK1 68/4885SMN1; SMN2 3488/4885GAA 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.