Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399308 | 0.78 | OXTR (0.51) | OXTRAVPR2AVPR1A | |
| SCHEMBL7398524 | 0.75 | OXTR (0.60) | OXTRAVPR2AVPR1A | |
| SCHEMBL7362816 | 0.75 | OXTR (0.85) | OXTRAVPR2AVPR1A | |
| SCHEMBL7494734 | 0.74 | OXTR (0.49) | OXTRAVPR2AVPR1A | |
| SCHEMBL7405740 | 0.73 | OXTR (0.45) | OXTRKMT2AAVPR2AVPR1A | |
| SCHEMBL7508507 | 0.71 | PDE4B (0.51) | OXTRKMT2AMEN1AVPR2AVPR1A | |
| SCHEMBL3882603 | 0.71 | TSHR (0.60) | OXTRKMT2AMEN1 | |
| SCHEMBL7399887 | 0.71 | OXTR (0.43) | OXTRKMT2AAVPR2AVPR1A | |
| SCHEMBL7506857 | 0.69 | MAPT (0.51) | OXTRKMT2AMEN1AVPR2AVPR1A | |
| SCHEMBL4750836 | 0.68 | GAA (0.74) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714299-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714299-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995002405-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-01-26 | — | — | WO | disclosed |