Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24788831 | 0.86 | CRBN (0.70) | CRBNDDB1TDP1ALDH1A1IKZF2 | |
| SCHEMBL19359372 | 0.83 | CRBN (0.73) | CRBNRAB9ADDB1KMT2AMEN1 | |
| SCHEMBL9631384 | 0.76 | CRBN (0.67) | CRBNRAB9ADDB1KMT2AMEN1 | |
| SCHEMBL19359233 | 0.74 | CRBN (0.63) | CRBNRAB9ADDB1KMT2AMEN1 | |
| SCHEMBL29923307 | 0.74 | CRBN (0.63) | CRBNRAB9ADDB1KMT2AMEN1 | |
| SCHEMBL25129766 | 0.71 | CRBN (0.54) | CRBNDDB1IKZF2IDH1IKZF3 | |
| SCHEMBL1499656 | 0.70 | CRBN (1.00) | CRBNDDB1TDP1ALDH1A1IKZF3 | |
| SCHEMBL6178113 | 0.70 | CRBN (1.00) | CRBNDDB1TDP1ALDH1A1IKZF3 | |
| SCHEMBL29943635 | 0.70 | CRBN (1.00) | CRBNDDB1TDP1ALDH1A1IKZF3 | |
| SCHEMBL6180704 | 0.70 | CRBN (1.00) | CRBNDDB1TDP1ALDH1A1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |