Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613757 | 0.83 | HRH3 (0.61) | HRH3MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8618958 | 0.76 | HRH3 (0.51) | HRH3MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8612116 | 0.76 | HRH3 (0.47) | HRH3CYP19A1MEN1KMT2AITGB3 | |
| SCHEMBL7400260 | 0.74 | MEN1 (0.49) | HRH3MEN1KMT2AITGB3ITGA2B | |
| Acetic Acid SCHEMBL8631159 | 0.72 | HRH3 (0.50) | HRH3MEN1KMT2AITGB3ITGA2B | |
| Acetic Acid SCHEMBL7399594 | 0.72 | HRH3 (0.50) | HRH3MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL3452878 | 0.72 | CHRM1 (0.48) | HRH3ITGB3ITGA2BMAPTKDM4E | |
| SCHEMBL8605444 | 0.72 | HRH3 (0.56) | HRH3CYP19A1ITGB3ITGA2BCYP3A4 | |
| SCHEMBL8613755 | 0.72 | ITGB3 (0.56) | HRH3MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL28784972 | 0.71 | HRH3 (0.57) | HRH3MEN1KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |