Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942824 | 0.86 | ITGB3 (0.63) | ITGB3ITGA2BFFAR4 | |
| Hydrochloric Acid SCHEMBL2948256 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BFFAR4 | |
| SCHEMBL7787414 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BKDM4EALDH1A1 | |
| SCHEMBL7787432 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BHRH3FFAR4 | |
| Hydrochloric Acid SCHEMBL7327151 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BFFAR4 | |
| SCHEMBL8612116 | 0.83 | HRH3 (0.47) | ITGB3ITGA2BHRH3KDM4EMEN1 | |
| SCHEMBL7788456 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2BKMT2A | |
| SCHEMBL7782716 | 0.82 | DRD2 (0.59) | ITGB3ITGA2BHRH3 | |
| SCHEMBL19134110 | 0.81 | FFAR4 (0.70) | ITGB3ITGA2BFFAR4 | |
| SCHEMBL7788365 | 0.81 | ITGB3 (0.62) | ITGB3ITGA2BFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786371-A | INHIBIT AGGREGATION OF BLOOD PLATELETS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-07-28 | — | — | US | disclosed |
| EP-0808306-A1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024586-A1 | NEW DERIVATIVES OF PYRIDINE OR PYRIDAZINE, PROCESS FOR PRODUCTION THEREOF AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-08-15 | — | — | WO | disclosed |