Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 19/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399209 | 0.88 | GHSR (0.47) | GHSROPRM1ACE | |
| SCHEMBL7401537 | 0.86 | GHSR (0.45) | GHSROPRM1ACE | |
| SCHEMBL9395015 | 0.83 | GHSR (0.52) | GHSROPRM1ACE | |
| SCHEMBL9391064 | 0.81 | GHSR (0.50) | GHSROPRM1ACE | |
| SCHEMBL7403198 | 0.80 | GHSR (0.47) | GHSROPRM1ACE | |
| SCHEMBL5615834 | 0.78 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL5666463 | 0.78 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL9391345 | 0.78 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL8343694 | 0.78 | TACR1 (0.59) | — | |
| SCHEMBL9389891 | 0.77 | GHSR (0.46) | GHSROPRM1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013696-A1 | SPIRO PIPERIDINES AND HOMOLOGS WHICH PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | claimed |
| EP-0820464-A2 | CYSTEINE PROTEASE INHIBITOR | Takeda Chemical Industries, Ltd. (JP) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996030395-A2 | CYSTEINE PROTEASE INHIBITOR | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |