Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 17/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399209 | 0.92 | GHSR (0.47) | GHSROPRM1ACEMMP2MMP9 | |
| SCHEMBL7400330 | 0.86 | GHSR (0.48) | GHSROPRM1ACE | |
| SCHEMBL9395015 | 0.80 | GHSR (0.52) | GHSROPRM1ACE | |
| SCHEMBL9391064 | 0.78 | GHSR (0.50) | GHSROPRM1ACE | |
| SCHEMBL8343307 | 0.78 | ITGB2 (0.50) | GHSRACEMMP2MMP9 | |
| SCHEMBL9389891 | 0.77 | GHSR (0.46) | GHSROPRM1ACE | |
| SCHEMBL9391345 | 0.77 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL5615834 | 0.77 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL5666463 | 0.77 | GHSR (0.51) | GHSROPRM1ACE | |
| Trifluoroacetic Acid SCHEMBL9391106 | 0.76 | GHSR (0.44) | GHSROPRM1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013696-A1 | SPIRO PIPERIDINES AND HOMOLOGS WHICH PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | claimed |
| WO-1994013696-A1 | SPIRO PIPERIDINES AND HOMOLOGS WHICH PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |