Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398025 | 0.91 | TSHR (0.47) | AOC3ITGB3ITGA2BROCK2PLOD2 | |
| SCHEMBL7397030 | 0.89 | AOC3 (0.47) | AOC3ITGB3ITGA2BROCK2PLOD2 | |
| SCHEMBL7403375 | 0.81 | AOC3 (0.48) | AOC3ITGB3ITGA2BROCK2PLOD2 | |
| SCHEMBL27462188 | 0.80 | HRH3 (0.54) | DRD2HRH3 | |
| SCHEMBL7393253 | 0.79 | ITGB3 (0.56) | PPARGPPARAITGB3ITGA2BALDH1A1 | |
| SCHEMBL7395114 | 0.76 | SMN1; SMN2 (0.55) | ITGB3ITGA2BALDH1A1TSHRCYP2D6 | |
| SCHEMBL8636929 | 0.75 | MAPT (0.48) | ITGB3ITGA2BROCK2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8837964 | 0.75 | ITGB3 (0.45) | AOC3ITGB3ITGA2BROCK2TSHR | |
| SCHEMBL8632825 | 0.75 | FAAH (0.42) | PPARGPPARAITGB3ITGA2BALDH1A1 | |
| SCHEMBL8681189 | 0.75 | ITGB3 (0.42) | ITGB3ITGA2BROCK2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |