Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.70 |
| ▸ | CTSB | P07858 | 7/20 | 0.67 |
| ▸ | CTSS | P25774 | 9/20 | 0.59 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400378 | 1.00 | CTSL (0.70) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400382 | 1.00 | CTSL (0.70) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7350460 | 0.84 | CTSL (0.86) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7350457 | 0.84 | CTSL (0.86) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7350465 | 0.84 | CTSL (0.86) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7400381 | 0.83 | CTSL (0.50) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7026935 | 0.83 | CTSL (0.77) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7031248 | 0.83 | CTSL (0.77) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7031241 | 0.83 | CTSL (0.77) | CTSLCTSBCTSSCTSKCTSH | |
| SCHEMBL7354034 | 0.82 | CTSL (0.83) | CTSLCTSBCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023222-A1 | IRREVERSIBLE CYSTEINE PROTEASE INHIBITORS CONTAINING VINYL GROUPS CONJUGATED TO ELECTRON WITHDRAWING GROUPS | KHEPRI PHARMACEUTICALS, INC. (US) | 1995-08-31 | — | — | WO | claimed |