Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.55 |
| ▸ | MMP9 | P14780 | 10/20 | 0.55 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 4/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400420 | 1.00 | MMP2 (0.55) | MMP2MMP9ADAMTS4MMP13MMP8 | |
| SCHEMBL3625854 | 0.87 | TDP1 (0.59) | MMP2MMP9ADAMTS4MMP13MMP8 | |
| SCHEMBL8072662 | 0.87 | SLC1A3 (0.54) | MMP2MMP9ADAMTS4MMP13MMP8 | |
| SCHEMBL5680766 | 0.86 | MMP2 (0.56) | MMP2MMP9ADAMTS4MMP13MMP8 | |
| SCHEMBL3623902 | 0.84 | SLC1A3 (0.54) | MMP2MMP9ADAMTS4MMP13MMP8 | |
| SCHEMBL18554330 | 0.83 | SLC1A3 (0.55) | MMP2MMP9ADAMTS4MMP13MMP8 | |
| SCHEMBL13570524 | 0.83 | MMP2 (0.58) | MMP2MMP9MMP13MMP8MMP1 | |
| SCHEMBL13570713 | 0.83 | MMP2 (0.58) | MMP2MMP9MMP13MMP8MMP1 | |
| SCHEMBL13570700 | 0.83 | MMP2 (0.58) | MMP2MMP9MMP13MMP8MMP1 | |
| SCHEMBL3622836 | 0.83 | SLC1A3 (0.55) | MMP2MMP9ADAMTS4MMP13MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0330239-B1 | Photosensitive composition | FUJI PHOTO FILM CO LTD (JP) | 1996-05-22 | — | — | EP | disclosed |
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5141838-A | Lithography printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0330239-A2 | Photosensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |