Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 8/20 | 0.48 |
| ▸ | MMP9 | P14780 | 7/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP7 | P09237 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3625854 | 0.86 | TDP1 (0.59) | SLC1A3SLC1A2SLC1A1TDP1MMP2 | |
| SCHEMBL13405434 | 0.85 | ALDH1A1 (0.46) | SLC1A3SLC1A2SLC1A1TDP1MEN1 | |
| SCHEMBL8050147 | 0.85 | ALDH1A1 (0.46) | SLC1A3SLC1A2SLC1A1TDP1MEN1 | |
| SCHEMBL7400420 | 0.84 | MMP2 (0.55) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL7400418 | 0.84 | MMP2 (0.55) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL8072662 | 0.83 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL13570524 | 0.83 | MMP2 (0.58) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL13570700 | 0.83 | MMP2 (0.58) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL13570713 | 0.83 | MMP2 (0.58) | SLC1A3SLC1A2SLC1A1MMP2MMP9 | |
| SCHEMBL18554330 | 0.80 | SLC1A3 (0.55) | SLC1A3SLC1A2SLC1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203420-A1 | HIV PROTEASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2010-07-07 | — | — | EP | disclosed |
| US-20100093811-A1 | HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2010-04-15 | — | — | US | disclosed |
| WO-2009042093-A1 | HIV PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009042094-A2 | HIV PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093811-A1 | HIV PROTEASE INHIBITORS | PRSS1, FURIN, SERPINB1 | SLC1A3 4146/4885SLC1A2 4486/4885SLC1A1 3919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.