Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7398991 | 0.99 | KDM4E (0.53) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9527422 | 0.84 | KDM4E (0.54) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9527542 | 0.83 | KDM4E (0.53) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL23475146 | 0.81 | ESR1 (0.52) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL27140298 | 0.81 | ESR1 (0.52) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9706744 | 0.80 | KCNH2 (0.55) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL13896891 | 0.79 | DRD2 (0.60) | KDM2B | |
| SCHEMBL7402234 | 0.79 | HRH3 (0.54) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9368539 | 0.79 | KCNH2 (0.54) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7397477 | 0.78 | HRH3 (0.53) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637303-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-08 | — | — | EP | claimed |
| WO-1993022302-A1 | N-ARYLOXY(THIO)ALKYL-AZACYCLOALKANES USEFUL AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-11-11 | — | — | WO | claimed |