Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406992 | 0.94 | SYK (0.49) | SYKMAPTPOLBMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8643329 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL8643309 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL6111432 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL7450972 | 0.84 | ITGB3 (0.47) | ITGB3ITGA2BITGAV | |
| SCHEMBL7969118 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BITGAV | |
| SCHEMBL7400722 | 0.83 | SYK (0.47) | SYKMAPTPOLBMAPK1L3MBTL1 | |
| Iodide SCHEMBL7403601 | 0.82 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL6111422 | 0.82 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL5027067 | 0.82 | ITGB3 (0.60) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |