Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645298 | 0.82 | ALOX15 (0.65) | ALOX15LMNAPTPN7HSD17B10HPGD | |
| SCHEMBL458062 | 0.81 | GSK3B (0.59) | ALOX15GSK3BPTPN1PTPN7ALDH1A1 | |
| SCHEMBL8555132 | 0.81 | ALOX15 (0.47) | ALOX15LMNAPTPN7HSD17B10HPGD | |
| SCHEMBL7406686 | 0.81 | GSK3B (0.46) | LMNAGSK3BHSD17B10HPGDALDH1A1 | |
| SCHEMBL5050018 | 0.79 | GSK3B (0.47) | LMNAGSK3BPTPN1ALDH1A1TSHR | |
| SCHEMBL6045418 | 0.76 | ALOX15 (0.54) | ALOX15LMNAPTPN7HSD17B10HPGD | |
| SCHEMBL2451027 | 0.76 | MEN1 (0.71) | LMNAGSK3BPTPN1 | |
| SCHEMBL9970986 | 0.75 | PLA2G2A (0.58) | GSK3BTSHRTHRATHRB | |
| SCHEMBL333513 | 0.75 | GSK3B (0.66) | GSK3BPTPN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5050000 | 0.74 | GSK3B (0.54) | GSK3BALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |