Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666220 | 0.79 | POLB (0.41) | POLBAPOBEC3GTDP1DDB1CRBN | |
| SCHEMBL8356079 | 0.76 | POLB (0.61) | POLBELANEAPOBEC3GTDP1DDB1 | |
| SCHEMBL12386349 | 0.76 | TDP1 (0.41) | POLBPKMAPOBEC3GTDP1KDM4E | |
| SCHEMBL16703411 | 0.76 | POLB (0.39) | POLBAPOBEC3GTDP1KDM4EDDB1 | |
| SCHEMBL793922 | 0.76 | FAAH (0.41) | POLBAPOBEC3GTDP1DDB1CRBN | |
| SCHEMBL8723165 | 0.76 | MGLL (0.41) | POLBAPOBEC3GTDP1KDM4ETP53 | |
| SCHEMBL4732529 | 0.75 | DDB1 (0.59) | POLBAPOBEC3GTDP1KDM4EDDB1 | |
| SCHEMBL7037359 | 0.74 | ELANE (0.38) | CYP11B2POLBELANEKDM4ETP53 | |
| SCHEMBL5906085 | 0.73 | TRPV1 (0.41) | CYP11B2POLBAPOBEC3GTDP1DDB1 | |
| SCHEMBL8354925 | 0.71 | ATM (0.47) | POLBELANEPKMKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |