Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809468 | 0.88 | HPGD (0.59) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL5727652 | 0.88 | HPGD (0.59) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL7030360 | 0.86 | HPGD (0.60) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL17078828 | 0.84 | ALDH1A1 (0.61) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL5655904 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL14698464 | 0.82 | MEN1 (0.54) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL7397800 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL28410476 | 0.78 | FOLH1 (0.46) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL8894983 | 0.78 | MEN1 (0.75) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL7898794 | 0.77 | MEN1 (0.55) | SMN1; SMN2LMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714299-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714299-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995002405-A1 | BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1995-01-26 | — | — | WO | disclosed |