SCHEMBL7401231

SCHEMBL7401231

CC(C)(O)C(CNC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(F)(F)C(=O)NCCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.60
CTRC Q99895 4/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7399564 0.84 ELANE (0.53) ELANECTRC
SCHEMBL7401233 0.84 ELANE (0.69) ELANECTRC
SCHEMBL7544232 0.81 ELANE (0.81) ELANECTRC
SCHEMBL7547030 0.80 ELANE (0.62) ELANECTRC
SCHEMBL8994526 0.80 ELANE (0.58) ELANECTRC
SCHEMBL8994476 0.80 ELANE (0.68) ELANECTRC
SCHEMBL8994472 0.77 ELANE (0.79) ELANECTRC
SCHEMBL7284339 0.76 ELANE (0.80) ELANECTRC
SCHEMBL7545819 0.76 ELANE (0.58) ELANECTRC
SCHEMBL7282527 0.75 ELANE (1.00) ELANECTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0636142-A1 LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY ZENECA LIMITED (GB) 1995-02-01 EP disclosed
WO-1993021209-A1 LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY ZENECA LIMITED (GB) 1993-10-28 WO disclosed