Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.53 |
| ▸ | CTRC | Q99895 | 6/20 | 0.42 |
| ▸ | CMA1 | P23946 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401231 | 0.84 | ELANE (0.60) | ELANECTRC | |
| SCHEMBL7399566 | 0.81 | ELANE (0.62) | ELANECTRCCMA1 | |
| SCHEMBL7547485 | 0.78 | ELANE (0.75) | ELANECTRC | |
| SCHEMBL8994467 | 0.77 | ELANE (0.55) | ELANECTRCCMA1 | |
| SCHEMBL7437149 | 0.77 | ELANE (0.50) | ELANECTRCCMA1 | |
| SCHEMBL7392881 | 0.75 | ELANE (0.56) | ELANECTRCCMA1 | |
| SCHEMBL7552480 | 0.72 | ELANE (0.64) | ELANECTRCCMA1 | |
| SCHEMBL7314760 | 0.72 | ELANE (0.58) | ELANECTRCCMA1 | |
| SCHEMBL8994556 | 0.72 | ELANE (0.68) | ELANECTRC | |
| SCHEMBL6556265 | 0.71 | ELANE (0.71) | ELANECTRCCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636142-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993021209-A1 | LACTAM PEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LIMITED (GB) | 1993-10-28 | — | — | WO | disclosed |