Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 8/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409221 | 0.84 | F10 (0.66) | NPSR1F10TPSAB1PRSS1F2 | |
| SCHEMBL6165371 | 0.81 | F2 (0.58) | NPSR1APEX1F10F2F7 | |
| SCHEMBL11887806 | 0.79 | APEX1 (0.64) | NPSR1APEX1CYP1A2TSHRTOP2A | |
| SCHEMBL7409276 | 0.79 | F10 (0.63) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL29613752 | 0.79 | GAA (0.60) | NPSR1APEX1CYP1A2TSHRTOP2A | |
| SCHEMBL22775824 | 0.79 | GAA (0.60) | NPSR1APEX1CYP1A2TSHRTOP2A | |
| SCHEMBL7070115 | 0.78 | NPSR1 (0.49) | NPSR1APEX1F10TPSAB1PRSS1 | |
| SCHEMBL4785390 | 0.78 | NPSR1 (0.75) | NPSR1APEX1CYP1A2TSHRTOP2A | |
| SCHEMBL16166279 | 0.77 | NPSR1 (0.54) | NPSR1APEX1F10TPSAB1PRSS1 | |
| SCHEMBL14510145 | 0.77 | NPSR1 (0.45) | NPSR1APEX1F10TPSAB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |