SCHEMBL7401545

SCHEMBL7401545

COc1cc(OC)c(C=O)cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.69
KDM4E B2RXH2 2/20 0.69
TSHR P16473 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
HPGD P15428 3/20 0.55
GAA P10253 3/20 0.55
GPR55 Q9Y2T6 1/20 0.55
ERN1 O75460 4/20 0.50
LMNA P02545 1/20 0.50
DPP4 P27487 1/20 0.49
PRKDC P78527 2/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPT P10636 2/20 0.46
NPC1 O15118 1/20 0.45
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10394357 0.92 ALDH1A1 (0.69) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL1187473 0.89 ALDH1A1 (0.65) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL15054285 0.88 ALDH1A1 (0.55) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL18851403 0.86 NPC1 (0.60) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL10849623 0.84 ALDH1A1 (0.86) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL11044996 0.84 ALDH1A1 (0.59) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL8188243 0.83 ALDH1A1 (0.57) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL22492691 0.82 PRKDC (0.72) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL3644816 0.82 ERN1 (0.54) ALDH1A1KDM4ETSHRTDP1HPGD
SCHEMBL4181333 0.82 ALDH1A1 (0.48) ALDH1A1KDM4ETSHRTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853652-B Sulfonium salt compound, preparation method and application thereof, and cationic UV (ultraviolet) curing adhesive 韦尔通科技股份有限公司 2023-08-29 CN disclosed
CN-114853652-A Sulfonium salt compound, preparation method and application thereof, and cationic UV (ultraviolet) curing adhesive 韦尔通(厦门)科技股份有限公司 2022-08-05 CN disclosed
EP-0714299-A4 1996-07-10 EP disclosed
EP-0714299-A1 BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS MERCK & CO. INC. (US) 1996-06-05 EP disclosed
WO-1995002405-A1 BENZOXAZINONE AND BENZOPYRIMIDINONE PIPERIDINYL TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1995-01-26 WO disclosed