Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836861 | 0.93 | ALDH1A1 (0.52) | ALDH1A1HPGDGAAGPR55KDM4E | |
| SCHEMBL692277 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDGAAGPR55KDM4E | |
| SCHEMBL31631787 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDGAAGPR55KDM4E | |
| SCHEMBL436131 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4ETSHRTDP1 | |
| SCHEMBL29636410 | 0.84 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ETSHRTDP1 | |
| SCHEMBL71268 | 0.84 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4ETSHRTDP1 | |
| SCHEMBL7401545 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDGAAGPR55KDM4E | |
| SCHEMBL15054285 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAGPR55KDM4E | |
| SCHEMBL30902485 | 0.81 | LMNA (0.47) | ALDH1A1HPGDKDM4ETSHRERN1 | |
| SCHEMBL20049020 | 0.80 | HMGCR (0.48) | ALDH1A1HPGDGAAGPR55KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798215-A | Benzothiophene compound, pharmaceutical composition, pharmaceutical preparation and application thereof | 北京福元医药股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-112979675-B | Small molecular sulfur-containing heterocyclic compound | 维眸生物科技（上海）有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20230114728-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | VenatoRx Pharmaceuticals, Inc. | 2023-04-13 | — | — | US | disclosed |
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-112979675-A | Small-molecule sulfur-containing heterocyclic compound | 维眸生物科技（上海）有限公司 | 2021-06-18 | — | — | CN | disclosed |
| WO-2021115495-A1 | SMALL-MOLECULE SULFUR-CONTAINING HETEROCYCLIC COMPOUND | 维眸生物科技（上海）有限公司 | 2021-06-17 | — | — | WO | disclosed |
| WO-2021108023-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | VenatoRx Pharmaceuticals, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |
| WO-2021108023-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | VenatoRx Pharmaceuticals, Inc. (US) | 2021-06-03 | — | — | WO | disclosed |
| US-10730849-B2 | Benzo[b]thiophene compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-08-04 | — | — | US | disclosed |
| US-10730849-B2 | Benzo[b]thiophene compounds as STING agonists | MERCK SHARP & DOHME CORP. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20090042874-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2009-02-12 | — | — | US | disclosed |
| US-20090042874-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2009-02-12 | — | — | US | disclosed |
| US-20090042874-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2009-02-12 | — | — | US | disclosed |
| WO-2008150848-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008150848-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2008-12-11 | — | — | WO | disclosed |
| US-6867230-B2 | Hygromycin A derivatives | PFIZER, INC. (US) | 2005-03-15 | — | — | US | disclosed |
| WO-2004099198-A1 | BENZOXAZINONE DERIVATIVES HAVING AFFINITY FOR 5- HT RECEPTORS, THEIR PREPARATION AND USE | GLAXO GROUP LIMITED (GB) | 2004-11-18 | — | — | WO | disclosed |
| US-20030045528-A1 | Hygromycin a derivatives | PFIZER INC. | 2003-03-06 | — | — | US | disclosed |
| EP-1287011-A1 | HYGROMYCIN A DERIVATIVES FOR THE TREATMENT OF BACTERIAL AND PROTOZOAL INFECTIONS | Pfizer Products Inc. (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001092280-A1 | HYGROMYCIN A DERIVATIVES FOR THE TREATMENT OF BACTERIAL AND PROTOZOAL INFECTIONS | PFIZER PRODUCTS INC. (US) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730849-B2 | Benzo[b]thiophene compounds as STING agonists | STING1, IRF3, CGAS | ALDH1A1 4174/4885HPGD 3265/4885GAA 250/4885 |
| US-20030045528-A1 | Hygromycin a derivatives | ERG28, HOGA1, MAN2B1 | ALDH1A1 485/4885HPGD 1235/4885GAA 403/4885 |
| US-20090042874-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | HTR5A, CRH, CYP17A1 | ALDH1A1 643/4885HPGD 1473/4885GAA 430/4885 |
| US-20230114728-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | ALDH1A1 2794/4885HPGD 2719/4885GAA 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.